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      Biocompatible unimolecular micelles obtained via the Passerini reaction as versatile nanocarriers for potential medical applications

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      Drug release (114.0Kb)
      Viability Assay (183.4Kb)
      Bacteriostatic activity (89.15Kb)
      Confocal laser scanning microscopic images of cellular uptake (1.054Mb)
      IR spectra (76.63Kb)
      RP-HPLC determination of octanol water partition coefficients of reduced and oxidized three-armed star-shaped block copolymers (71.33Kb)
      3 UV/VIS spectra of the encapsulation of Orange II in DCM by reduced and oxidized star-shaped block copolymers P4, P6, P7 and P8, (106.7Kb)
      UV/VIS spectra of the encapsulation of water insoluble Para Red in water by reduced and oxidized star-shaped block copolymers P4, P6, P7 and P8. (100.2Kb)
      UV/VIS spectra (below) of the encapsulation of Reichardt‘s Dye in DCM by reduced and oxidized star-shaped block copolymers P4, P6, P7 and P8 showing different wavelength maxima, due to their different polarity and due to the solvatochromism effect of the encapsulated dye. (98.48Kb)
      Aabsorbance of Orange II in water (75.83Kb)
      Absorbance of Orange II in DCM (74.70Kb)
      Graphical abstract (474.3Kb)
      Publication date
      2018-06-20
      Creators
      Travanut, Alessandra
      Metadata
      Show full item record
      Description
      Drug loading and encapsulation efficiency, In vitro drug release study, Cell culture, Viability assay, Bacterial susceptibility assay, Cellular uptake study.
      External URI
      • https://rdmc.nottingham.ac.uk/handle/internal/355
      DOI
      • http://doi.org/10.17639/nott.351
      Related publication DOI
      • 10.1021/acs.biomac.8b00592
      Subjects
      • Micelles
      • Chemical reactions
      • Drug carriers (Pharmacy)
      • Nanocapsules
      • Microencapsulation
      • Micelles
      • Chemistry, Pharmaceutical
      • Drug Carriers
      • Nanotechnology
      • Drug Compounding
      • Passerini-3CR
      • Subjects Allied to Medicine::Pharmacology, toxicology & pharmacy::Pharmacy
      • R Medicine::RS Pharmacy and materia medica
      Divisions
      • University of Nottingham, UK Campus::Faculty of Science::School of Pharmacy
      Deposit date
      2018-06-20
      Corporate creators
      • Karlsruhe Institute of Technology
      Data type
      Experimental data
      Contributors
      • Romero, Manuel
      • Alexander, Cameron
      • Oelmann, Stefan
      • Meier, Michael A. R.
      Funders
      • Other
      • Engineering and Physical Sciences Research Council (EPSRC)_ Next Generation Biomaterials Discovery
      Grant number
      • EP/N03371X/1, EP/H005625/1, EP/N006615/1and EP/L013835/1
      Collection dates
      • January 2018 - March 2018
      Coverage
      • University of Nottingham
      • Boots Science Building
      Data collection method
      Experimental data: Drug loading and Encapsulation Efficiency, In Vitro Drug Release Study, Viability Assay, Bacterial susceptibility assay, Cellular Uptake Study
      Provenance / lineage
      http://files.nottingham.ac.uk/SitePages/default.aspx
      Resource languages
      • en
      Copyright
      • Cameron Alexander
      Publisher
      University of Nottingham

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