University of Nottingham logo, linking to repository homepage
      View Item 
      • Nottingham Research Data Management Repository
      • University of Nottingham Research Data Management Service
      • Public Research Data
      • View Item
      • Nottingham Research Data Management Repository
      • University of Nottingham Research Data Management Service
      • Public Research Data
      • View Item
      JavaScript is disabled for your browser. Some features of this site may not work without it.

      Discovery of a novel polymer for human pluripotent stem cell expansion and multilineage differentiation - Supporting data 1

      Thumbnail
      View/Open
      DSpace data.zip (65.54Mb)
      Publication date
      2015-06-08
      Creators
      Celiz, Adam
      Smith, James
      Denning, Chris
      Alexander, Morgan
      Metadata
      Show full item record
      Description
      A scalable and cost-effective synthetic polymer substrate that supports robust expansion and subsequent multilineage differentiation of human pluripotent stem cells (hPSCs) with defined commercial media is presented. This substrate can be applied to common cultureware and used off-the-shelf after long-term storage. Expansion and differentiation of hPSCs are performed entirely on the polymeric surface, enabling the clinical potential of hPSC-derived cells to be realized. Data presented herein includes time-of-flight secondary-ion mass spectrometry (ToF-SIMS), X-ray photoelectron spectroscopy (XPS), water contact angle (WCA) measurements, fluorescence microscopy, cell electrophysiology, nuclear magnetic resonance (NMR) spectroscopy, gel permeation chromatography (GPC). Please note that this data set is in two parts, the second part of which can be found here: http://doi.org/10.17639/nott.16
      External URI
      • https://rdmc.nottingham.ac.uk/handle/internal/15
      DOI
      • http://doi.org/10.17639/nott.12
      Related publication DOI
      • 10.1002/adma.201501351
      Links
      • http://onlinelibrary.wiley.com/doi/10.1002/adma.201501351/full
      • http://doi.org/10.17639/nott.16
      • http://doi.org/10.17639/nott.12
      Subjects
      • Polymers in medicine
      • Stem cells
      • Human cell culture
      • Cell differentiation
      • Stem Cells
      • Cell Culture Techniques
      • Cell Differentiation
      • Polymers
      • high throughput; human pluripotent stem cells; materials discovery; polymer microarrays; stem cell differentiation; ToF-SIMS; XPS; WCA; Cell Microscopy; Electrophysiology; NMR and GPC datasets.
      • JACS Subjects::Medicine and Dentistry::Clinical medicine
      • JACS Subjects::Biological Sciences::Molecular biology, biophysics & biochemistry
      • JACS Subjects::Biological Sciences::Biology::Cell biology
      • JACS Subjects::Physical sciences::Chemistry::Analytical chemistry
      • JACS Subjects::Physical sciences::Chemistry::Organic chemistry::Polymer chemistry
      • JACS Subjects::Physical sciences::Materials science
      • JACS Subjects::Engineering::Chemical, process & energy engineering::Chemical engineering::Biochemical engineering
      • Library of Congress Subject Areas::T Technology::TP Chemical technology::TP1080 Polymers and polymer manufacture
      • Library of Congress Subject Areas::R Medicine::R Medicine (General)::R855 Medical technology. Biomedical engineering. Electronics
      Divisions
      • Faculties, Schools and Departments::University of Nottingham, UK Campus::Faculty of Medicine and Health Sciences::School of Medicine
      Research institutes and centres
      • Research institutes and centres::University of Nottingham, UK Campus::Biomolecular Sciences, Centre for
      Deposit date
      2015-06-04
      Data type
      Raw data files for ToF-SIMS, XPS, WCA, Cell Microscopy, Electrophysiology, NMR and GPC datasets.
      Funders
      • Funders::Engineering & Physical Sciences Research Council
      • Funders::Wellcome Trust
      • Funders::Biotechnology & biological Sciences Research Council
      • Funders::Medical Research Council
      • UK Regenerative Medicine Platform
      • British Heart Foundation
      • Heart Research UK
      • National Centre for the Replacement, Refinement and Reduction of Animals in Research
      Grant number
      • EP/H045384/1
      Parent project
      • 'Future-Proof' Synthetic Surfaces for the Automated Manufacture of Human Pluripotent Stem Cells (EP/H045384/1)
      Collection dates
      • 01/10/2010 - 01/06/2015
      Data collection method
      ToF-SIMS (SurfaceLab - ION-TOF), XPS (CASA XPS), WCA, Cell Microscopy (IMSTAR), Electrophysiology, NMR (BRUKER) and GPC (Shimadzu) datasets.
      Legal and ethical issues
      A patent has been filed in relation to the work described herein.
      Provenance / lineage
      See methods in manuscript (DOI: 10.1002/adma.201501351)
      Resource languages
      • en
      Copyright
      • University of Nottingham
      Publisher
      University of Nottingham

      Browse

      All of Nottingham Research Data Management RepositoryBy Issue DateAuthorsTitlesSubjectsThis CollectionBy Issue DateAuthorsTitlesSubjects

      My Account

      UoN Login

      Arkivum Files

      My Downloads

      Statistics

      Most Popular ItemsStatistics by CountryMost Popular Authors
       

      Research @ The University of Nottingham

      King's Meadow Campus

      Lenton Lane

      Nottingham, NG7 2NR

      For further information and policies refer to https://www.nottingham.ac.uk/library/research/research-data-management/index.aspx

      For further information and policies refer to Policies

      For information on accessibility refer to https://www.nottingham.ac.uk/utilities/accessibility/dspace.aspx

      and the Accessibility Statement