Browsing by Author "7dde938b-8b0d-4346-a1f3-7ab08aeec12f"

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Chain length affects pancreatic lipase activity and the extent and pH–time profile of triglyceride lipolysis

Gershkovich, Pavel; Benito, Paloma (The University of Nottingham, 2016-07-01)

Triglycerides (TG) are one of the most common excipients used in oral lipid-based formulations. The chain length of the TG plays an important role in the oral bioavailability of the co-administered drug. Fatty acid (FA) ...
In vitro lipolysis/microsomal metabolism approach for the prediction of oral bioavailability of BCS II drugs in lipidic formulations

Gershkovich, Pavel; Benito, Paloma (The University of Nottingham, 2016-08-24)

Lipidic formulations (LFs) are increasingly utilized for the delivery of drugs that belong to class II of the Biopharmaceutics Classification System (BCS). The current work proposes, for the first time, the combination ...